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Job Function:
Discovery & Pre-Clinical/Clinical DevelopmentJob Sub Function:
Biological ResearchJob Category:
People LeaderAll Job Posting Locations:
Cambridge Massachusetts United States of AmericaJob Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.
Learn more at are searching for the best talent for a Senior Manager Vector Biology to be in Cambridge MA.
Purpose:
We are seeking an experienced Senior Manager to oversee a multidisciplinary team responsible for advancing viral vector biology vector design improvements assay development and optimization of lentiviral vectors for in vivo cell this role you will provide technical leadership and strategic direction to drive the teams research and development efforts with a focus on enhancing cell-specific transduction capabilities.
You will be responsible for:
Manage a team of scientists and engineers focused on viral vector biology vector design and assay development
Oversee the teams work to improve lentiviral vector design and performance for in vivo cell targeting including:
Identifying optimal target molecules and cell surface receptors for efficient vector binding and entry
Leveraging expertise in cell biology to understand and enhance vector-cell interactions for improved cell type-specific transduction
Designing and validating assays to characterize vector tropism cell binding internalization and transduction efficiency
Develop and implement strategies to optimize lentiviral vectors for specific cell type transduction
Ensure the team designs and validates robust assays to test key assumptions about vector biology cell targeting and overall performance
Collaborate cross-functionally with other R&D teams to integrate vector innovations into cell and gene therapy programs
Provide technical leadership and strategic direction to drive the teams research and development efforts
Manage budgets timelines and resources to deliver on team objectives
Foster a culture of innovation continuous improvement and strong scientific rigor
Qualifications:
Advanced degree (PhD preferred) in molecular biology virology bioengineering or a related field with 6-8 years of relevant industry experience in cell and gene therapy with a strong background in viral vector development
Deep expertise in lentiviral vector biology design and optimization for in vivo applications including strong knowledge of cell biology principles to enable efficient cell targeting
Extensive experience developing and validating assays to characterize vector tropism cell binding internalization and transduction efficiency
Demonstrated track record of leveraging cell biology insights to engineer improved cell-targeting capabilities of viral vectors
Thorough understanding of cell surface receptor biology cell signaling pathways and intracellular trafficking mechanisms to inform vector design and optimization
Proven track record of leading multidisciplinary teams and delivering tangible R&D outcomes
Excellent problem-solving project management and communication skills
Ability to translate complex scientific concepts including cell biology into actionable strategies
Strong collaborative mindset and ability to work effectively cross-functionally
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please email the Employee Health Support Center () or contact AskGS to be directed to your accommodation resource.
Required Skills:
Preferred Skills:
Big Data Management Data Reporting Data Savvy Developing Others Drug Discovery Development Good Clinical Practice (GCP) Inclusive Leadership Industry Analysis Leadership Molecular Diagnostics Operational Excellence Pharmaceutical Microbiology Product Knowledge Project Reporting Scientific Research Strategic Thinking Sustainability Team ManagementThe anticipated base pay range for this position is :
$137000.00 - $235750.00Additional Description for Pay Transparency:
Subject to the terms of their respective plans employees are eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)). Subject to the terms of their respective policies and date of hire employees are eligible for the following time off benefits:Senior Manager
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